Fern B Overdosage

Overdose: Vitamin B₁: Thiamine has a broad therapeutic range. Very high doses (over 10 g) have a ganglion-blocking effect, similar to that of curare, and suppress the conduction of nerve impulses.
Vitamin B₆: The toxic potential of Vitamin B₆ can be considered as very low. Long-term intake (>6-12 months) of a daily dosage >50 mg Vitamin B₆ may however, cause peripheral sensory neuropathy and other sensorial neuropathy syndromes. These symptoms improve gradually upon vitamin discontinuation.
Prolonged overdosage of Vitamin B₆, for longer than 2 months and >1g daily, may lead to neurotoxic effects.
Neuropathies with ataxia and sensitivity disorders, cerebral convulsions with EEG changes as well as in individual cases, hypochromic and seborrhoeic dermatitis have been described after administration of more than 2 g daily.
Vitamin B₁₂: Allergic reactions, eczematous skin changes and a benign form of acne have been observed after high parenteral doses (in rare cases also after oral doses).
Treatment: Increase Fluids: B vitamins are water soluble, adding more fluid to the body helps remove vitamin B before they undergo absorption. Health care provider may suggest consuming a large quantity of water in a short amount of time to flush excessive B vitamins out of the bloodstream. At the hospital, patient may receive intravenous fluid, or IV, to get more fluids into the system.
Induced Vomiting: In some cases, induced vomiting is necessary if the patient ingest a large dose of vitamin B. This practice requires supervision of a health care provider to avoid any adverse effects. Vomiting is induced by an oral medication. If overdose is severe, patient may need a gastric lavage, in which a plastic tube is inserted down to the throat and into the stomach, flushing out all content of the stomach.
Charcoal: Activated charcoal can be administered at the hospital to absorb toxic levels of vitamins, especially if patient ingest large amount of multiple vitamins or other substances at once. This treatment is given orally to absorb the excessive B vitamins in the body. The charcoal, along with the B vitamins is excreted through stool, patient may experience diarrhoea in the process.